Table 2 The genotype and allele frequencies of miR-155-5p gene rs767649 polymorphisms in patients with essential hypertension
Genotype/allele | HC (n = 250) | Hypertension (n = 250) | OR (95% CI) | P value |
|---|---|---|---|---|
TT | 99 (39.60) | 126 (50.40) | 1 | – |
TA | 118 (47.20) | 87 (34.80) | 0.579 (0.395–0.849) | 0.005 |
AA | 33 (13.20) | 37 (14.80) | 0.881 (0.514–1.509) | 0.644 |
Dominant model | Â | Â | Â | Â |
TT | 99 (39.60) | 126(50.40) | 1 | Â |
TA + AA | 151 (60.40) | 124 (49.60) | 0.645 (0.453–0.920) | 0.015 |
Recessive model | Â | Â | Â | Â |
TT + TA | 217 (86.80) | 213 (85.20) | 1 |  |
AA | 33 (13.20) | 37 (14.80) | 1.142 (0.689–1.894) | 0.606 |
Additive model | Â | Â | Â | 0.126 |
T | 316 (63.20) | 339 (67.80) | 1 | - |
C | 184 (36.80) | 161 (32.20) | 0.816 (0.628–1.059) | 0.126 |
PHWE | 0.816 | Â | Â | Â |